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br torsion is a urological emergency that may occur at
2020-05-22

torsion is a urological emergency that may occur at any age. To establish blood flow surgical detorsion is required in most cases while detorsion can sometimes be achieved by hand assistance. Regardless of the correction method 2 phases (I/R) negatively affect germ cells. The torsion phase decreas
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hop over to here br Materials and methods br Results
2020-05-22

Materials and methods Results Discussion The main finding of the present study is that selective ETA and dual ETA/ETB receptor blockade markedly improve endothelium-dependent vasodilatation in patients with type 2 diabetes and vascular complications. The magnitude of improvement did not dif
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In recent years there has been
2020-05-22

In recent years, there has been much interest within the endothelin community regarding the possibility that ETA and ETB receptors may form homo- and heterodimers. Heterodimerization of endothelin receptors may provide an explanation for the results mentioned in the previous paragraph and might also
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Two isoforms of intracellular ER
2020-05-22

Two isoforms of intracellular ER, ERα, and ERβ, after binding to estrogens and translocate to the nucleus, activate some transcription factors and signaling pathways. The deregulation of estrogenic pathways can elevate transcriptional activity contributed to the development of cancer. Expression of
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br E intracellular localization br Regulation
2020-05-22

E1 intracellular localization Regulation of E1 by other post-translational modifications Concluding remarks Acknowledgments We apologize to those whose work was not included because of space considerations or whose papers were unintentionally omitted. We thank Dr Peter Bullock (Tufts Uni
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Introduction Psoralea corylifolia L Leguminosae is a well kn
2020-05-22

Introduction Psoralea corylifolia L. (Leguminosae) is a well-known traditional Chinese medicine, and it has been widely used for the treatment of various diseases like bronchial asthma, leucopenia, vitiligo and psoriasis in East Asian countries (Zhang et al., 1990). Previous studies have reported t
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In contrast to DDR the role of oligomerization and
2020-05-22

In TW-37 to DDR1, the role of oligomerization and/or clustering of DDR2 in mediating its interactions with collagen is less understood. Current data show that in DDR2, like in DDR1, (i) dimerization [7] and higher-order oligomerization of its ECD [11], [22] enhance its binding to collagen, and (ii)
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In astrocytes mitogen activated protein
2020-05-22

In astrocytes, mitogen-activated protein kinases (MAPKs) are activated after OGD-induced ischemic injury (Yung and Tolkovsky, 2003, Niu et al., 2009) and they regulate induction of AQP expression (Arima et al., 2003, McCoy and Sontheimer, 2010). It is well known that MAPKs, including extracellular s
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br Experimental procedures br Introduction Perfluorooctane s
2020-05-22

Experimental procedures Introduction Perfluorooctane sulfonate (PFOS) is an anthropogenic compound with high thermal, chemical and biological stability, which makes it a perfect ingredient for many industrial applications (Kissa, 2001). Nevertheless, these characteristics also mean that PFOS i
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Interferon IFN induces formation of a
2020-05-21

Interferon (IFN)-γ induces formation of a heterotetrameric, IFN-gamma-activated inhibitor of translation (GAIT) complex in human monocytic Epinephrine HCl mg (Mazumder et al., 2003a, Sampath et al., 2004). The complex binds a bipartite stem-loop element in the 3′UTR of vascular endothelial growth f
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Elevated production of cysLTs in asthma and rhinitis
2020-05-21

Elevated production of cysLTs in Anastrozole synthesis and rhinitis in general and aspirin-sensitive disease in particular10, 11, 26, 27 has been implicated in causing epithelial cell activation and excessive mucus secretion, which characterize these diseases.2, 28 It is of particular interest, the
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In rats exposed to day of nicotine withdrawal
2020-05-21

In rats exposed to 1 day of nicotine withdrawal (24 h after the last nicotine administration) we expected a decrease of general locomotor activity and a decrease of global striatal dopamine release, which were assessed in a previous study following 14 days of nicotine exposure and 24 h of nicotine w
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br Substrate Specificity Discrimination and Binding Energy I
2020-05-21

Substrate Specificity, Discrimination, and Binding Energy In nmda receptor to catalytic efficiency, which can be gauged in reference to an absolute scale of ‘catalytic perfection’ 10, 11, specificity is a relative concept because it requires comparison between given alternative substrates. In fac
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CYP contributes to the metabolism of
2020-05-21

CYP450 contributes to the metabolism of more than 90% of currently available drugs (Shapiro and Shear, 2002). Currently, CYP1A is the most studied xenobiotic-metabolizing isoform in fish and is often used as a biomarker for early effects of pollutants in aquatic organisms (Havelkova et al., 2007). T
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Expression of both CH H and CYP B by lymphoid
2020-05-21

Expression of both CH25H and CYP7B1 by lymphoid stromal tlr4 is required for the synthesis of 7α,25-OHC in lymphoid tissues and the correct positioning of B cells. Production of EBI2 ligand by hematopoietically derived cells appears limited [24] but may occur under some circumstances, given that bo
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